Applying for jobs with misdemeanors

So I am a college student right now and I made some mistakes. I have a very good resume and everything the only problem is I have a few misdemeanor charges on my record. (underage drinking and drug possession) My question is how should I go about applying for jobs? Should I be upfront about my history in my cover letters / interview or wait until they do a background check? I don’t want to put a ton of effort into a compony just to find out I get turned down but I also don’t want to be rejected too quickly.

usa jobs
usa jobs resume
usa hotel jobs
usajobs
usa jobs federal government
usa job in ksa
usa jobs
usa jobs login
usa jobs gov
usajobs.gov
www.usajobs.gov
usajobs.com
usajobs
usajobs.gov official