What's a week of PTO worth?

Obviously I know I can calculate the actual value of 5 days of PTO, but when considering a job, what's it worth to you?

I've been offered a position that will pay me around $22k more, but only offers 10 days of PTO. I've worked at companies that only offer 10 days, and it basically makes it impossible to take any sort of vacation if you plan to spend time with family around the holidays.

This new company also doesn't match 401Ks, which I've never really heard of. This company does couple hundred million in review annually.

22k is quite a bit of a difference, so am I just making too big of a deal over a couple days and no 401k match?

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