Is it a deal breaker if they ask "Do you have any questions for me?" And I answer "No I don't." ?

Is this a deal breaker for most jobs?

I can see it being a deal breaker for some of the more serious careers but what about the other positions that don't necessarily require too much experience?

usa jobs
usa jobs resume
usa hotel jobs
usajobs
usa jobs federal government
usa job in ksa
usa jobs
usa jobs login
usa jobs gov
usajobs.gov
www.usajobs.gov
usajobs.com
usajobs
usajobs.gov official